B Cell Receptor Signaling. Tomohiro Kurosaki

B Cell Receptor Signaling


B.Cell.Receptor.Signaling.pdf
ISBN: 9783319261317 | 231 pages | 6 Mb


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B Cell Receptor Signaling Tomohiro Kurosaki
Publisher: Springer International Publishing



Burger1 and Nicholas Chiorazzi2. Signaling through the B cell antigen receptor (BCR) results in rapid increases in tyrosine phosphorylation on a number of proteins. Follicular B cell survival requires signaling from BAFFR, a receptor for BAFF and the B cell antigen receptor (BCR). Doi: 10.1016/j.semcancer.2013.09. Basal B-cell receptor signaling in B lymphocytes: mechanisms of regulation and role in positive selection, differentiation, and peripheral survival. Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma. Intrinsic differences in the initiation of B cell receptor signaling favor responses of human IgG(+) memory B cells over IgM(+) naive B cells. The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy. Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia. A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. B cell receptor signaling in chronic lymphocytic leukemia. Signalling through the B cell receptor (BCR) is central to the development and maintenance of B cells.





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